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郭霞生
发布人:佚名 信息来源:本站原创  发布时间:2015年08月07日 点击数量:

Xiasheng Guo, Associate Professor
 
地址:江苏省南京市汉口路22号 南京大学声学研究所,210093
电话: 83594395
电子邮件: guoxs@nju.edu.cn

教育背景和工作经历
1999.9-2003.6    南京大学电子科学与工程系      本科
2003.9-2008.6    南京大学声学研究所           博士
2008.7-2010.8    南京大学电子科学与工程系      博士后
2010.9-2011.12 南京大学物理学院            讲师
2011.12-今    南京大学物理学院             副教授

研究领域:
生物医学超声、超声微纳/米操控、超声生物效应、高强度聚焦超声
 
承担的科研项目:
1、 基于超常声辐射力的微气泡操控研究( 国家自然科学基金,20015.1-2018.12)
2、自聚焦超声的声场调控及精细焦域研究( 国家自然科学基金,2012.1-2014.12)
3、基于声学超常材料的高强度聚焦超声精细焦域调控研究(江苏省自然科学基金,2012.1-4014.12)

教学情况:
1、数字信号处理(本科三年级)

发表论文目录(“*”表示为通讯作者)
[1]   Chen, T., Fan, T. B., Zhang, W., Qiu, Y. Y., Tu, J., Guo, X. S., and Zhang, D. (2014). "Acoustic characterization of high intensity focused ultrasound fields generated from a transmitter with a large aperture," J Appl Phys 115.
[2]   Geng, H., Fan, T. B., Zhang, Z., Tu, J., Guo, X. S., Li, F. Q., and Zhang, D. (2014). "Tissue lesion induced by a spherical cavity transducer," Acta Phys Sin-Ch Ed 63.
[3]   Guo, G. P., Lu, L., Ji, H. F., Ma, Y., Dong, R., Tu, J., Guo, X. S., Qiu, Y. Y., Wu, J. R., and Zhang, D. (2015). "Low intensity pulse ultrasound stimulate chondrocytes growth in a 3-D alginate scaffold through improved porosity and permeability," Ultrasonics 58, 43-52.
[4]   Guo, G. P., Lu, L., Yin, L. L., Tu, J., Guo, X. S., Wu, J. R., Xu, D., and Zhang, D. (2014). "Mechanical and dynamic characteristics of encapsulated microbubbles coupled by magnetic nanoparticles as multifunctional imaging and drug delivery agents," Phys Med Biol 59, 6729-6747.
[5]   Guo, X. S., Li, Q., Zhang, Z., Zhang, D., and Tu, J. (2013a). "Investigation on the inertial cavitation threshold and shell properties of commercialized ultrasound contrast agent microbubbles," J Acoust Soc Am 134, 1622-1631.
[6]   Guo, X. S., Lin, Z., Tu, J., Liang, B., Cheng, J. C., and Zhang, D. (2013b). "Modeling and optimization of an acoustic diode based on micro-bubble nonlinearity," J Acoust Soc Am 133, 1119-1125.
[7]   Guo, X. S., Yang, D., Zhang, D., Li, W. G., Qiu, Y., and Wu, J. R. (2009). "Quantitative evaluation of fracture healing process of long bones using guided ultrasound waves: A computational feasibility study (L)," J Acoust Soc Am 125, 2834-2837.
[8]   Guo, X. S., Zhang, D., and Gong, X. F. (2007). "Evaluation of ultrasonic scattering in human cancellous bone by using a binary mixture model," Phys Med Biol 52, 29-40.
[9]   Guo, X. S., Zhang, D., and Wu, J. R. (2010). "Quantitative evaluation of contact stiffness between pressed solid surfaces using dual-frequency ultrasound," J Appl Phys 108.
[10]  Guo, X. S., Zhang, D., Yang, D., Gong, X. F., and Wu, J. R. (2008). "Comment on "Three-dimensional finite element modeling of guided ultrasound wave propagation in intact and healing long bones," [J. Acoust. Soc. Am. 121(6), 3907-3921 (2007)]," J Acoust Soc Am 123, 4047-4050.
[11]  Guo, X. S., Zhang, D., and Zhang, J. (2012). "Detection of fatigue-induced micro-cracks in a pipe by using time-reversed nonlinear guided waves: A three-dimensional model study," Ultrasonics 52, 912-919.
[12]  Li, F. Q., Wang, H., Zeng, D. P., Fan, T. B., Geng, H., Tu, J., Guo, X. S., Gong, X. B., Zhao, C. L., Wang, Z. L., Zhang, D., and Wang, Z. B. (2013a). "Sub-wavelength ultrasonic therapy using a spherical cavity transducer with open ends," Appl Phys Lett 102.
[13]  Li, Q., Matula, T. J., Tu, J., Guo, X. S., and Zhang, D. (2013b). "Modeling complicated rheological behaviors in encapsulating shells of lipid-coated microbubbles accounting for nonlinear changes of both shell viscosity and elasticity," Phys Med Biol 58, 985-998.
[14]  Li, Y., Tu, J., Liang, B., Guo, X. S., Zhang, D., and Cheng, J. C. (2012). "Unidirectional acoustic transmission based on source pattern reconstruction," J Appl Phys 112.
[15]  Li, Y. L., Liu, Z. B., Ma, Q. Y., Guo, X. S., and Zhang, D. (2010). "Two-Dimensional Lorentz Force Image Reconstruction for Magnetoacoustic Tomography with Magnetic Induction," Chinese Phys Lett 27.
[16]  Liang, B., Guo, X. S., Tu, J., Zhang, D., and Cheng, J. C. (2010). "An acoustic rectifier," Nat Mater 9, 989-992.
[17]  Lin, Z., Guo, X., Tu, J., Ma, Q., Wu, J., and Zhang, D. (2015). "Acoustic non-diffracting Airy beam," J Appl Phys 117, 104503.
[18]  Lin, Z., Guo, X. S., Tu, J., Cheng, J. C., Wu, J. R., and Zhang, D. (2014). "Acoustic focusing of sub-wavelength scale achieved by multiple Fabry-Perot resonance effect," J Appl Phys 115.
[19]  Liu, Y., Guo, X. S., Da, Z., Zhang, D., and Gong, X. F. (2011). "Imaging Cracks in Bones Using Acoustic Nonlinearity: A Simulation Study," Acta Acust United Ac 97, 728-733.
[20]  Liu, Z., Guo, X., Tu, J., and Zhang, D. (2014). "Variations in temperature distribution and tissue lesion formation induced by tissue inhomogeneity for therapeutic ultrasound," Ultrasound Med Biol 40, 1857-1868.
[21]  Liu, Z. B., Fan, T. B., Guo, X. S., and Zhang, D. (2010). "Effect of Tissue Inhomogeneity on Nonlinear Propagation of Focused Ultrasound," Chinese Phys Lett 27.
[22]  Lu, L., Ji, H. F., Guo, G. P., Guo, X. S., Tu, J., Qiu, Y. Y., and Zhang, D. (2015). "Ultrasonic enhancement of the porosity of alginate scaffold," Acta Phys Sin-Ch Ed 64, 8.
[23]  Sun, J. M., Yu, J., Guo, X. S., and Zhang, D. (2013). "Study of nonlinear acoustic field of high intensity focused ultrasound by the fractional wave," Acta Phys Sin-Ch Ed 62.
[24]  Tu, J., Hwang, J. H., Chen, T., Fan, T. B., Guo, X. S., Crum, L. A., and Zhang, D. (2012). "Controllable in vivo hyperthermia effect induced by pulsed high intensity focused ultrasound with low duty cycles," Appl Phys Lett 101.
[25]  Wang, L., Tu, J., Guo, X. S., Xu, D., and Zhang, D. (2014). "Microstreaming velocity field and shear stress created by an oscillating encapsulated microbubble near a cell membrane," Chinese Phys B 23, 7.
[26]  Wang, X. F., Matula, T. J., Ma, Y., Liu, Z., Tu, J., Guo, X. S., and Zhang, D. (2013). "Finite element modeling of acoustic wave propagation and energy deposition in bone during extracorporeal shock wave treatment," J Appl Phys 113.
[27]  Xiao, Q., Wang, J., Guo, X. S., and Zhang, D. (2013). "Nonlinear interaction between ultrasound and solid rough interface," Acta Phys Sin-Ch Ed 62.
[28]  Xu, B., Dou, H. J., Tao, K., Sun, K., Ding, J., Shi, W. B., Guo, X. S., Li, J. Y., Zhang, D., and Sun, K. (2011). ""Two-in-One" Fabrication of Fe3O4/MePEG-PLA Composite Nanocapsules as a Potential Ultrasonic/MRI Dual Contrast Agent," Langmuir 27, 12134-12142.
[29]  Yang, D., Zhang, D., Guo, X. S., Gong, X. F., and Fei, X. B. (2008). "A multi-dimensional approach for describing internal bleeding in an artery: implications for Doppler ultrasound guiding HIFU hemostasis," Phys Med Biol 53, 4983-4994.
[30]  Yu, J., Chen, C. Y., Chen, G., Guo, X. S., Ma, Y., Tu, J., and Zhang, D. (2014). "Real-Time Monitoring and Quantitative Evaluation of Cavitation Bubbles Induced by High Intensity Focused Ultrasound Using B-Mode Imaging," Chinese Phys Lett 31.
[31]  Zhang, C. B., Cao, H. L., Li, Q., Tu, J., Guo, X. S., Liu, Z., and Zhang, D. (2013). "Enhancement Effect of Ultrasound-Induced Microbubble Cavitation on Branched Polyethylenimine-Mediated Vegf(165) Transfection with Varied N/P Ratio," Ultrasound Med Biol 39, 161-171.
[32]  Zhang, C. B., Liu, Z., Guo, X. S., and Zhang, D. (2011). "Correlation between microbubble-induced acoustic cavitation and hemolysis in vitro," Chinese Phys B 20.
[33]  Zhang, K., Chen, H. R., Guo, X. S., Zhang, D., Zheng, Y. Y., Zheng, H. R., and Shi, J. L. (2015). "Double-scattering/reflection in a Single Nanoparticle for Intensified Ultrasound Imaging," Sci Rep-Uk 5, 11.
 
授权发明专利:
  1. 刘洋;章东;郭霞生;2012, 用于长骨分析的超声导波参数测量方法, 专利授权号: ZL201010239035.2
  2. 程建春;梁彬;屠娟;郭霞生;章东;2012,一种声二极管及检测声二极管的系统,专利授权号: ZL201110028240.9
  3. 郭霞生;章东;刘洋;2012,一种双频超声检测界面接触强度的方法,专利授权号: ZL201010253665.5
 
教科书和专著章节:
1、 章东,郭霞生,马青玉,屠娟;医学超声基础, 科学出版社, 2014年3月, 55.1万字.

 
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